If you don't have a physical TPM device, you can enable emulation of the feature through your system firmware, known as the “fTPM.” Ryzen machines support fTPM, but on some systems, enabling it causes bizarre, periodic stutters that cause the entire machine to hang up briefly. These stutters don't just interrupt gameplay but any activity at all on the machine including videos, music, or just moving the mouse around.
AMD announced that it believed it had found the root cause of the problem early in March, but said that firmware updates wouldn't be ready before early May. Indeed, some vendors have published updates that purport to resolve the problem. Well now, AMD's come out and said that it has shipped fixed firmware along with AGESA version 126.96.36.199 to the motherboard manufacturers. Essentially, it's in their hands now.
With that in mind, if you're experiencing this stutter, or if you simply want to upgrade to Windows 11 and don't want to suffer the stutter, head to your motherboard manufacturer's website and look for the latest BIOS update. Not every vendor has updated every board—notably, this author's ASRock X570 Taichi hasn't gotten an update yet—but it looks like the majority of ASUS, Gigabyte, and MSI boards using X570 and B550 chipsets have been updated. Let's hope the rest can get the new firmware fixed up soon.